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Carsten Gründker Selected Research

Osteoprotegerin

6/2008Expression of osteoprotegerin and receptor activator of nuclear factor-kappaB ligand (RANKL) in HCC70 breast cancer cells and effects of treatment with gonadotropin-releasing hormone on RANKL expression.
9/2003Raloxifene concurrently stimulates osteoprotegerin and inhibits interleukin-6 production by human trabecular osteoblasts.

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Carsten Gründker Research Topics

Disease

43Neoplasms (Cancer)
11/2023 - 01/2002
30Breast Neoplasms (Breast Cancer)
11/2023 - 10/2004
19Ovarian Neoplasms (Ovarian Cancer)
05/2023 - 02/2002
14Endometrial Neoplasms (Endometrial Cancer)
05/2023 - 01/2002
12Triple Negative Breast Neoplasms
11/2022 - 01/2010
6Neoplasm Metastasis (Metastasis)
11/2023 - 12/2011
3Bone Resorption
09/2003 - 01/2002
2Carcinoma (Carcinomatosis)
09/2023 - 05/2023
2Pancreatic Neoplasms (Pancreatic Cancer)
01/2017 - 09/2011
1Endometrial Hyperplasia
01/2021
1Glioblastoma (Glioblastoma Multiforme)
01/2017
1Adenocarcinoma
09/2011

Drug/Important Bio-Agent (IBA)

33Gonadotropin-Releasing Hormone (GnRH)FDA Link
01/2021 - 01/2002
22LHRH Receptors (Gonadotropin-Releasing Hormone Receptor)IBA
01/2021 - 01/2002
11Estrogens (Estrogen)FDA Link
05/2023 - 01/2008
11lysine(6)-doxorubicin LHRHIBA
07/2019 - 09/2002
10Estrogen ReceptorsIBA
11/2023 - 04/2008
10Doxorubicin (Adriamycin)FDA LinkGeneric
06/2014 - 05/2002
10His(5)-Trp(7)-Tyr(8)- LHRHIBA
01/2013 - 03/2002
9Triptorelin Pamoate (Trelstar)FDA Link
01/2008 - 02/2002
7Growth Factor ReceptorsIBA
01/2017 - 01/2002
6Progesterone Receptors (Progesterone Receptor)IBA
01/2018 - 01/2010
5afimoxifene (hydroxytamoxifen)IBA
11/2023 - 10/2005
5TamoxifenFDA LinkGeneric
11/2023 - 11/2005
5GTP-Binding Proteins (G-Protein)IBA
09/2023 - 01/2018
5Estrogen Receptor alphaIBA
09/2023 - 11/2004
5Protein Tyrosine PhosphatasesIBA
01/2017 - 01/2002
4Caspase 3 (Caspase-3)IBA
05/2011 - 05/2004
4cetrorelix (Cetrotide)FDA Link
07/2004 - 02/2002
3Hormones (Hormone)IBA
11/2023 - 04/2010
3resazurinIBA
11/2022 - 01/2013
3Deoxyglucose (2 Deoxy D glucose)IBA
07/2019 - 01/2013
3Estrogen Receptor Modulators (Antiestrogen)IBA
12/2014 - 04/2008
3MelatoninIBA
04/2010 - 11/2005
3Cytotoxins (Cytolysins)IBA
01/2009 - 05/2004
3RANK LigandIBA
06/2008 - 01/2002
3NF-kappa B (NF-kB)IBA
01/2008 - 01/2002
3Oncogene Proteins (Oncogene Protein)IBA
02/2007 - 01/2002
3Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
02/2007 - 01/2002
2Selective Estrogen Receptor Modulators (SERM)IBA
11/2023 - 12/2021
2Glucose (Dextrose)FDA LinkGeneric
12/2021 - 01/2020
2Lactic Acid (Lactate)FDA LinkGeneric
12/2021 - 01/2020
2GonadotropinsIBA
01/2021 - 11/2012
2Small Interfering RNA (siRNA)IBA
12/2020 - 07/2012
2Proteins (Proteins, Gene)FDA Link
01/2019 - 08/2009
2Cysteine (L-Cysteine)FDA Link
01/2019 - 06/2016
2Gefitinib (Iressa)FDA Link
02/2017 - 11/2012
2AntibodiesIBA
07/2015 - 02/2014
2Protein Isoforms (Isoforms)IBA
07/2015 - 02/2014
2human ERBB2 proteinIBA
02/2015 - 07/2012
2human KISS1 proteinIBA
02/2014 - 12/2010
2Messenger RNA (mRNA)IBA
07/2012 - 03/2002
2DNA (Deoxyribonucleic Acid)IBA
12/2011 - 05/2002
2Melatonin Receptors (Melatonin Receptor)IBA
04/2010 - 08/2009
2Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA
04/2010 - 08/2009
2ElementsIBA
04/2010 - 08/2009
2OsteoprotegerinIBA
06/2008 - 09/2003
2Estradiol (Delestrogen)FDA LinkGeneric
04/2007 - 11/2004
2Epidermal Growth Factor (EGF)IBA
11/2006 - 10/2005
1Phenobarbital (Luminal)FDA Link
11/2023
1rho GTPase-activating proteinIBA
12/2020
1GTP Phosphohydrolases (GTPases)IBA
12/2020
1EnzymesIBA
12/2020
1Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA
10/2020
1betaIG-H3 protein (keratoepithelin)IBA
10/2020
1ProteomeIBA
10/2020
1Connective Tissue Growth FactorIBA
10/2020
1Zinc Finger E-box-Binding Homeobox 1IBA
10/2020
1Adenosine Triphosphate (ATP)IBA
07/2019
1pegvisomantFDA LinkGeneric
06/2018
1Somatotropin Receptors (Growth Hormone Receptor)IBA
06/2018
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
01/2018
1Metformin (Glucophage)FDA LinkGeneric
04/2017
1Trastuzumab (Herceptin)FDA Link
02/2017
1S100 Calcium-Binding Protein A4IBA
06/2016
1Estriol (Epiestriol)IBA
12/2014
1PlatinumIBA
06/2014
1liposomal doxorubicin (Doxil)FDA Link
06/2014
1taxaneIBA
06/2014
1Topotecan (Hycamtin)FDA LinkGeneric
06/2014
1Acetates (Acetic Acid Esters)FDA Link
06/2014
1perifosineIBA
11/2012
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
07/2012
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2011
1Thrombospondin 1IBA
07/2011
1Chemokine ReceptorsIBA
12/2010
1Progestins (Progestagens)IBA
06/2010
1salicylhydroxamic acid (SHAM)IBA
04/2010
1p38 Mitogen-Activated Protein KinasesIBA
01/2010
1Phosphotransferases (Kinase)IBA
08/2009
1Mitogen-Activated Protein KinasesIBA
08/2009
1Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
04/2009
1Plasminogen Activators (Plasminogen Activator)IBA
04/2009
1Tissue Plasminogen Activator (Alteplase)FDA Link
04/2009

Therapy/Procedure

16Therapeutics
11/2023 - 02/2005
8Drug Therapy (Chemotherapy)
06/2018 - 09/2002
6Aftercare (After-Treatment)
02/2017 - 09/2002
2Radiotherapy
02/2014 - 04/2007
1Intraperitoneal Injections
07/2011
1Intravenous Administration
01/2009